There’s a mountain of glucosamine for dogs reviews out there and numerous products featuring them. Yet, only a handful of these fulfilled our team’s strict quality criteria and made it on this list of the best glucosamine for dogs.

To find out which ones we picked, look at the table below!

Quick Glance at Our Top Picks

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Anxious Pet Hip & Hop Supplement Bars

Best Bar Supplement

  • Veterinarian-formulated
  • cGMP-certified
  • GMO and gluten-free
  • Natural hypoallergenic flavor
  • Easy to dose

Dasuquin Soft Chews With MSM

Most Potent Supplement

  • Many active ingredients
  • Practical bottle sizes
  • Size-specific formulas
  • More absorbable chondroitin
  • Contains ASU (unsaponifiables)

Honest Paws Mobility Soft Chews

Best CBD-Infused Chews

  • Natural ingredients
  • High CBD content
  • Organic and GMO-free
  • Extensive CoA available
  • Convenient for all dog sizes

Austin and Kat Bakko's Hip and Joint Chews

Special Formula Hip Pain

  • Human-grade ingredients
  • NASC-Quality Seal
  • Free from preservatives
  • With L-Carnitine and vitamin E
  • Contains ginger

Doggie Dailies Advanced Hip & Joint Soft Chews

Best for Cartilage and Connective Tissues

  • Enhances the immune system
  • Improves digestion
  • Rich in hyaluronic acid
  • Packed with vitamins C and E
  • Rich mix of ingredients

PetHonesty Strength Joint Support Chews

  • All-natural ingredients
  • Easy to dose for all breed sizes
  • Produced by strict GMP standards
  • Contains balanced collagen
  • With fish oil and organic turmeric

Cosequin Nutramax Laboratories Joint Supplement

Best for Large Breeds

  • Rich in minerals
  • Packed with vitamins
  • Tasty chicken flavor
  • Vet-researched ingredients
  • Produced in the US

cbdMD CBD Hip & Joint Soft Chews

Best Soft Chews

  • GMP-standardized manufacturing
  • Available lab test results
  • Products based on breed size
  • Contains omega-3 oils
  • Free form GMOs

Charlotte's Web Hip & Joint Chews

Best Natural Option

  • All-natural ingredients
  • NASC-certified
  • Broad-spectrum CBD
  • Available third-party test results
  • Resealable bag keep chews fresh

Zesty Paws Mobility Bites

  • Easy to dose
  • No artificial preservatives
  • Organic hemp seed oil
  • Enhances mobility
  • Eases pains and aches

The Best Glucosamine Products in Detail

Without further delay, let’s check out what the best bird feed brands have to offer.

Anxious Pet Hip & Hop Supplement Bars

star 10

Best Bar Supplement

  • Type: Supplement bars
  • Size: 5 packs x 1.8 oz (2” x 3”)
  • Flavor: Natural peanut butter & banana flavor
  • Glucosamine: 1500mg proprietary glucosamine blend
  • Ingredients: With MSM, willow bark, Yucca Schidigera, Contains Cat’s Claw and Devil’s Claw extracts

The Anxious Pet Hip & Hop Supplement Bars are a unique glucosamine joint supplement for dogs, providing a convenient, natural way to give your dog efficient joint support.

Indeed, you don’t need to think of how to sneak glucosamine in dogs’ food with these bars. Just give this peanut butter and a banana-flavored treat to your dog, and they’ll have all they need for their immune system to fight arthritis, joint reparation, and overall joint health.

Numerous Anxious Pet Supplement Bars reviews confirm the efficacy of these ingredients-rich bars. Moreover, MSM, Cat’s Claw, Devil’s Claw, willow bark, Yucca Schidigera, and organic turmeric are also added into the mix.

Each Anxious Pet bar contains 3 smaller bars. Meaning, there are exactly 15 doses of the glucosamine blend in the 5 affordable packs that they are offering. Besides the richness and the budget-friendliness of these Kansas-made bars, we liked the fact that they are handmade, as well as grain, soy, preservative, and GMO-free. Plus, they provide more value in our eyes due to their natural coloring and flavors.

Also, our Hip & Hop Supplement Bars with glucosamine review uncovered that this product is manufactured according to Current Good Manufacturing Practice regulations (cGMP) — FDA-issued regulations for production practices and facilities.


  • + Veterinarian-formulated
  • + cGMP-certified
  • + GMO and gluten-free
  • + Natural hypoallergenic flavor
  • + Easy to dose


  • Not many discount options

Dasuquin Soft Chews With MSM

star 9.8

Most Potent Supplement

  • Type: Chews
  • Size: 84ct and 150ct
  • Flavor: Natural
  • Glucosamine: 900mg glucosamine HCL per chew
  • Feature: 350mg sodium chondroitin sulfate per chew, 800mg MSM, 90mg ASU powder, green tea, and rosemary extract

The Dasuquin brand offers 2 versions of the soft chewable glucosamine for dogs with MSM according to breed size — small to medium (up to 60lbs) and large breeds (>60lbs). These packagings make it easier to manage the glucosamine chondroitin dosage for dogs that are different in size. Add the bundle discounts to this equation and you’ll get the perfect multi-pet offer.

The MSM Dasuquin Soft Chews for Large Dogs formula is incredibly rich and jam-packed with essential ingredients. Yet, interestingly enough, ASU and green tea extract are also added into the mix.

As we’ll explain in the Buyer’s Guide below, ASU is a vegetable extract that combines avocado and soybean oil. Likewise, this combo stimulates the healing processes in both bone and joints. Green tea acts on the same antioxidative level as ASU, boosting the already powerful formulations of dog joint supplements from Dasuquin.

Other Glucosamine Supplements by Dasuquin

The wide palette of glucosamine products of Dasuquin includes 7 different types of soft chews and tablets, all of them in 2 breed-size versions. But, whether as tablets or as chews, the unique Dasuquin blend of powerful active ingredients aids in the treatment of hip dysplasia and arthritis.


  • + Many active ingredients
  • + Practical bottle sizes
  • + Size-specific formulas
  • + More absorbable chondroitin
  • + Contains ASU (unsaponifiables)


  • Not available from the Dasuquin webpage

Honest Paws Mobility Soft Chews

star 9.9

Best CBD-Infused Chews

  • Type: Chews
  • Size: 30 chews per bag
  • Flavor: Poultry
  • Glucosamine: 500mg glucosamine, 50mg chondroitin, and 40mg CBD per chew
  • Feature: GMO, wheat, soy, and corn-free
  • Testing: Extensive third-party tests available

CBD can be a powerful ally in the fight against pain-inducing ailments, including arthritis. What’s more, Mobility Honest Paws CBD chews for pain reviews from pet owners show that the rich 40mg of CBD per chew has an immediate effect on their pets, making them more lively and confident in motion — an obvious sign of decreased pain.

In addition to the glucosamine and chondroitin, the chews also contain 15mg of Boswellia Serrata in powder, which is proven to reduce pain and swelling as well. Thus, improving the range of motions in dogs and alleviating joint stiffness.

Owners also claim that dogs like the poultry flavor, as per many Honest Paws chews reviews. Another thing worth mentioning in our Honest Paws review is the policy of the brand. Namely, this brand is firmly against using GMO and non-organic compounds. As such, they exclusively use natural ingredients in every product they offer, and Mobility Chews are no exception. These chews contain organic glucosamine suitable for dogs and 100% all-natural ingredients.

Yet, why is this so important?

The latest GMO statistics show that GMO food is associated with heavy pesticide use. Hence, choosing a non-GMO product for your dog also means not feeding it with harmful chemicals.


  • + Natural ingredients
  • + High CBD content
  • + Organic and GMO-free
  • + Extensive CoA available
  • + Convenient for all dog sizes


  • Some complaints on slow delivery

Austin and Kat Bakko's Hip and Joint Chews

star 9.9

Special Formula Hip Pain

  • Type: Treats
  • Size: 6.6oz (188g)
  • Flavor: Duck
  • Glucosamine: 35mg glucosamine chondroitin blend
  • Feature: 10mg full-spectrum CBD per bite, contains L-Carnitine, and Green-Lipped Mussel
  • Feature: With ginger and nutritional yeast

Austin and Kat hemp-infused CBD biscuits contain proprietary blends and high-quality CBD oil, hence why they ranked so high on our list. All of their ingredients are pure and human-grade (in other words, they are safe for human consumption).

Best known as Bakko’s Hip and Joint Chews, these biscuits contain 10mg of full-spectrum CBD oil per bite. Like all Austin and Kat CBD pet products, they have powerful anti-inflammatory and analgesic properties. Apart from that, these chewables exhibit strong antioxidative effects due to their rich ingredient list, which contains ginger and beneficial fatty acids like Salmon oil, organic flaxseed oil, and Green-lipped Mussel.

Numerous Austin and Kat CBD-infused dog biscuits reviews highlight that the Hip and Joint formula is simply insatiable for dogs. Better yet, their effects are easily noticeable even upon first use, making it perfect for impatient pet parents. All in all, with these tasty and effective bites, you can rest assured that your dog is getting all the essential nutrients to maintain its bone, cartilage, and connective tissue health.

Other Austin & Kat Products that Have Glucosamine

Brady’s Senior Blend is yet another Austin and Kat CBD-infused dog biscuits specialized for dogs over 6 years of age. These contain more inactive ingredients than the chews for adults, with the exception of the hemp content which is the same.

Bakko’s Hip and Joint Tincture, on the other hand, specialize in glucosamine- and hemp-infused functional oil for back, joint, and hip issues in dogs. The New Zealand GLM and the organic Ceylon cinnamon help reduce joint stiffness and soreness.

Moreover, the Austin and Kat CBD oil review reveals the chews also contain Astaxanthin — an exceptionally powerful antioxidant that is 6000 times more potent than vitamin C.


  • + Human-grade ingredients
  • + NASC-Quality Seal
  • + Free from preservatives
  • + With L-Carnitine and vitamin E
  • + Contains ginger


  • Not suitable for small dog breeds

Doggie Dailies Advanced Hip & Joint Soft Chews

star 9.6

Best for Cartilage and Connective Tissues

  • Type: Soft chews
  • Size: 225ct
  • Flavor: Chicken, peanut butter
  • Glucosamine: 100mg glucosamine per chew
  • Feature: 50mg chondroitin per chew, 100mg MSM per 4g of chew, and omega fatty acids

This Doggie Dailies Hip and Joint supplement is designed to improve the joint health of your dog. Not only that but it also helps improve digestion, the immune system, and cardiovascular health.

With 100mg of glucosamine and 50mg chondroitin, these chews may not be as concentrated as other formulas. Nevertheless, the presence of other beneficial compounds boosts their effectiveness. Namely, the hyaluronic acid, the omega 3 & 6 fatty acids, MSM, and vitamins C and E work together to improve cartilage integrity. They also repair damaged tissue, along with the many minerals, vitamins, and enzymes that are also featured in the ingredient list.

Doggie Dailies also don’t shy away from including more exclusive ingredients like Yucca Schidigera, CoQ10, or salmon, and cod liver oil in their chews. Given that this is a quite rich mix of ingredients, some doggies need time to get used to it.

Yet, there’s no need for worry since the chews can be easily crumbled in your dog’s regular food until they become accustomed.


  • + Enhances the immune system
  • + Improves digestion
  • + Rich in hyaluronic acid
  • + Packed with vitamins C and E
  • + Rich mix of ingredients


  • Contains wheat
  • Some dogs may need time to get used to the chews

PetHonesty Strength Joint Support Chews

star 10
  • Type: Chews
  • Size: 60ct
  • Flavor: Natural chicken flavor
  • Glucosamine: 700mg glucosamine HCL (per 2 chews)
  • Feature: 300mg MSM (PurforMSM) & High Green-Lipped Mussel (500mg)
  • Feature: APHIS-Approved, SQF-certified

We picked the PetHonesty Pure Mobility Max Strength Joint Support chews because of their highly concentrated formula of active ingredients for adult dogs — primarily glucosamine and chondroitin. These two substances not only synergize well to maintain your dog’s overall joint health but also work wonders to rebuild damaged joints and hips. Plus, they work together with other ingredients present in the formula, such as methylsulfonylmethane (MSM) and the balanced collagen.

A lot of PetHonesty reviews from customers attest to the effectiveness of these ingredients for boosting the health of your furry friend. But what about joint pain? Namely, arthritis prevents the joint’s natural lubrication from working, causing most of your pet’s joint aches. Yet, with these chews, you needn’t worry as they contain the most Green-Lipped Mussel (500mg) we’ve found thus far!

Together with the glucosamine and the fish oil for dogs, these chews will help cushion your dog’s joints and restore the lost lubricating fluid. What’s more, the Max Strength supplement includes 400mg of organic turmeric and Yucca Schidigera extract — giving your dog an extra hand to fight inflammation and to move without pain.

Other Glucosamine Supplements by PetHonesty

If you are looking to spice things up with hemp extracts, the PetHonesty Hemp Hip and Joint supplement for dogs might be a better choice for you.

There are two available Hemp Mobility snacks: the adult and the senior formula. There’s another, more potent option too — the PetHonesty Advanced Hip and Joint Chews.


  • + All-natural ingredients
  • + Easy to dose for all breed sizes
  • + Produced by strict GMP standards
  • + Contains balanced collagen
  • + With fish oil and organic turmeric


  • Shipments may take longer than expected

Cosequin Nutramax Laboratories Joint Supplement

star 9.7

Best for Large Breeds

  • Type: Soft chews
  • Sizes: 60ct, 120ct, and 240ct
  • Flavor: Chicken
  • Glucosamine: 600mg glucosamine HCL
  • Feature: 300mg sodium chondroitin sulfate, 400mg MSM per chew, & 70mg omega-3 fatty acids

Filled with the patented, scientifically-researched Nutramax Cosequin’s Maximum Strength with MSM and Omega 3’s Soft Chews is a top-notch canine glucosamine supplement. Apart from the proven quality of the main joint-active glucosamine and chondroitin, Cosequin contains about 400mg of MSM per chew.

Cosequin customers confirm that these chicken-flavored soft chews are insatiable for dogs with any level of food-pickiness. The Omega 3 fatty acids play a role in the restoration of the joints’ cushioning. Yet, that is not all! They also help your doggie maintain healthy and shiny fur.

Other Glucosamine Supplements by Cosequin

Chewable tablets are available in four different formulas:

  • enriched with Boswellia Serrata extract (Active Lifestyle)
  • with Green-Lipped Mussel (Hip and Joint Support)
  • with multivitamins and minerals (Advanced Plus)
  • with MSM (Maximum Strength)

Furthermore, dogs below 25lbs also have the option of Cosequin Minis Maximum Strength — soft chews with suitable concentrations of glucosamine for small dogs.


  • + Rich in minerals
  • + Packed with vitamins
  • + Tasty chicken flavor
  • + Vet-researched ingredients
  • + Produced in the US


  • Not practical for dogs under 10lbs

cbdMD CBD Hip & Joint Soft Chews

star 9.8

Best Soft Chews

  • Type: Treats
  • Size: 30ct bottle
  • Flavor: Bacon
  • Glucosamine: 50mg glucosamine HCL and 30mg of chondroitin per chew
  • Feature: 150, 300, or 600mg CBD and 50mg MSM per chew

cbdMD offers three types of glucosamine-infused, bacon-flavored chews, all with equal concentrations of glucosamine, MSM, and chondroitin per chew. However, as numerous cbdMD for dogs reviews can attest, each strength provides different benefits (and effects) due to their varying CBD concentration.

cbdMD Hip and Joint Chews of 300mg are perfect for medium-sized breeds — hence why they are the most popular. For their long-lasting effects, we can probably thank the quality of cbdMD’s oil, which is deemed one of the best quality CBD oils for dogs on the market.

Renowned for its highly effective anti-inflammatory, and analgesic (pain relief) effects, these cbdMD dog treats are infused with CBD oil isolate that is completely THC-free and pure. What we liked the most with the 300mg cbdMD Hip and Joint Chews was this brand’s transparency. As we detailed in our cbdMD review, the lab test results are made public, which will offer peace of mind to any pet owner.

A lot of cbdMD dog treats reviews also praise the brand for using healthy omega 3 fatty acids that help speed up the recovery processes. In this particular cbdMD product, they come from flaxseed, fish oil, coconut, and MCT oil.

When looking at the whole picture — the transparency, the purity, the discount on offers, and the generous 60-day money-back guarantee — it becomes obvious why cbdMD’s treats are referred to as one of the best glucosamine chews for dogs.


  • + GMP-standardized manufacturing
  • + Available lab test results
  • + Products based on breed size
  • + Contains omega-3 oils
  • + Free form GMOs


  • Only one flavor choice
  • Same glucosamine and chondroitin concentrations

Charlotte's Web Hip & Joint Chews

star 10

Best Natural Option

  • Type: Chews
  • Size: 30ct, 60ct
  • Flavor: Chicken
  • Glucosamine: 125mg glucosamine HCL (per 4g of chew)
  • Feature: 5mg of broad-spectrum hemp extract, 30mg chondroitin, and 75mg of turmeric root powder

In the re-sealable Charlotte’s Web Hip & Joint chews for dogs bag you will find the “dynamic duo” in the fight against arthritis — namely, glucosamine and chondroitin. The vegetable-derived glucosamine HCl and the bovine chondroitin sulfate account for some intense joint repair in dogs.

Moreover, the turmeric root powder in these chews also helps stop joint inflammation in its tracks. In addition to the glucosamine and turmeric for dogs mix, Charlotte’s Web also uses its world-renowned broad-spectrum CBD. Thus ensuring immediate comfort and pain-relief for our furry family members. High-quality hemp oil is used to prevent and treat many dog ailments — hence why it is rapidly becoming a normal part of basic dog care.

In Charlotte’s Web chews mix, CBD provides instant pain relief and improves mobility, which can be read in almost any Charlotte’s Web dog chews review. What’s more, you can’t go wrong with the natural chicken flavor that these chews offer. It is indisputably the best flavor for administering a glucosamine routine even the pickiest of dogs.

There’s a good chance that your best friend will simply love these glucosamine treats, seeing how there are multiple Charlotte’s Web dog treats reviews on the internet that confirm their tastiness.


  • + All-natural ingredients
  • + NASC-certified
  • + Broad-spectrum CBD
  • + Available third-party test results
  • + Resealable bag keep chews fresh


  • Not suitable for dogs under 10lbs

Zesty Paws Mobility Bites

star 9.9
  • Type: Chews
  • Size: 90ct
  • Flavor: Chicken
  • Glucosamine: 450mg glucosamine hydrochloride per chew
  • Feature: 125mg chondroitin per chew, 400mg MSM (OptMSM®) per chew, and 400mg of organic hemp seed powder

There are more than 320 Zesty Paws Mobility Bites reviews that attest to the quality and popularity of this glucosamine product. We chose the Zesty Paws’ Hemp Elements Mobility Bites because of their efficiency in dealing with pain and joint discomfort, particularly in the case of arthritis.

Indeed, with 400mg of hemp seed powder and another 100mg of organic hemp seed oil per chew, it is one of the most potent hemp mixes of all glucosamine supplements for dogs. What’s more, our Zesty Paws Mobility Bites review revealed that they are also rich in glucosamine, MSM, and chondroitin.

As for the plant-based active ingredients, Boswellia, Turmeric, and the 35mg of concentrated curcuminoids are there to fight off inflammation and swelling. Moreover, they are all wrapped in every dogs’ favorite — natural chicken flavor.

However, these were not the only reasons we ranked Zesty Paws as one of the top products. The pure, all-natural ingredients, as well as the absence of any artificial preservatives and grains, were what attracted us to this brand. If you are not quite sure whether these chewables are the right choice for you, there is also a 10ct tryout package that will help form your decision.

Other Glucosamine Supplements by Zesty Paws

In total, Zesty Paws offers 3 types of glucosamine-infused chews: the Regular, Zesty Paws Advanced Mobility Bites, and the Hemp Elements formula.

All of these are manufactured with several patented mixes of active ingredients including:

  • Qmin+TM — Curcuminoids (95%)
  • OptiMSM® — Highly purified MSM
  • Bioperine® — Black pepper extract

Besides this, flavor choices include chicken, duck, and bacon.


  • + Easy to dose
  • + No artificial preservatives
  • + Organic hemp seed oil
  • + Enhances mobility
  • + Eases pains and aches


  • May take time for dog's stomach to get used to them


Our Methodology for Choosing the Best Products

A good pet parent is a wary pet parent! Indeed, when it comes to picking a food supplement from a sea of honest and not-so-honest retailers, one cannot be too careful. What’s more, the Food and Drug Administration (FDA) is not yet regulating the pet supplement market.

Hence, responsible pet owners need to research the quality of the products and check customer recommendations to find the right supplements. To help you in your quest, we decided to share the criteria we used to choose the best ones. These were the following:


Researching what exactly you’ll be feeding your dog should be your first priority. This is why the transparency of a brand is of grave importance. Namely, transparency means publicly displaying information concerning the source of the glucosamine used in the products and the complete list of active and inactive ingredients.

By our criteria, the best brand of glucosamine for dogs is the one that offers an additional scoop into the entire manufacturing process, origins of most of the ingredients, purity levels, and related information.

We’ve also looked into each company’s reputation, customer friendliness, and general terms of sale. To get to the bottom of this, we used testimonials of both professional teams and customers on several online platforms, just to make sure!

Ingredient Mix

Active Ingredients

The right formula should contain at least 2 ingredients that help protect the integrity of dog joints and restore the damage that has been done. Moreover, we’ve paid particular attention to the richness of the ingredient list. And not just in terms of variety, but also in terms of concentration.

So, what exactly are active ingredients?

Any ingredient that is scientifically proven to have a positive influence on joint and hip health in these products is an active ingredient. Chondroitin and glucosamine are the most popular active components of almost every glucosamine supplement, frequently accompanied by Methylsulfonylmethane (MSM).

Inactive Ingredients

Yes, you guessed it right, these compounds do nothing to improve our pet’s joint health. So, why include them at all?

Well, inactive ingredients ensure the stability of the glucosamine formula, and they also play a role in its shelf life. Furthermore, they aid the absorption process of the active ingredients in your dog’s body (carriers).

In other words, even the best type of glucosamine will not be effective if the inactive formula mix doesn’t support its absorption. What’s more, inactive ingredients are frequently the cause of allergy episodes in dogs. Therefore, high-quality glucosamine supplements usually don’t contain soy, wheat, grain, or other allergenic compounds.

Quality and Safety

In our quest for the highest-quality glucosamine products for dogs, we searched for hard proof of both safety and quality, such as national certificates and accreditations. As you can see in the reviews above, most products we picked were produced in a facility that abides by Good Manufacturing Practices (GMP).

The quality of some of them is even regulated by the Animal and Plant Health Inspection Service (APHIS), and some have an SQF (Safe Quality Food) certificate. Moreover, some have even received the quality seal of the National Animal Supplement Council (NASC).

In addition, most of the glucosamine chondroitin for dogs items on our list are produced in FDA-approved facilities.

Value and Price

Probably the most important criterion for many customers is the value-to-price ratio. Namely, we estimated the value by comparing different aspects of the product in question, such as:

  • The diversity of the ingredient list and their respective concentrations
  • The purity of the substances and their safety
  • The quantity and the number of doses that can be administered

Customer Reviews and Experience

Whether sincere or bogus, glucosamine for dogs reviews always relay information on possible issues with certain supplements.

We combed through public complaints of many a brand to pick the ones that offer glucosamine that is easy to dose, administer, and is effective. Nevertheless, we are well aware that this doesn’t provide the complete picture — hence why we also focused on scam investigation, shipment and delivery policies, and refund options.

Choosing the Right Supplement

Buying Guide

It seems like a simple enough task, but it can get a bit overwhelming when you realize how many products are out there. So first, let’s understand what glucosamine is and why it is essential for your dog.

The Chemical Formula of Glucosamine

Much like glucosamine supplements intended for human consumption, those for dogs can be found in two different forms:

  • glucosamine sulfate
  • glucosamine hydrochloride (HCL)

Glucosamine hydrochloride is usually combined with chondroitin sulfate to increase absorption. Glucosamine sulfate, on the other hand, is often “unaccompanied.”

So, what is the best type of glucosamine for dogs between these two?

Researchers proved that glucosamine sulfate is more easily absorbed in the body than glucosamine HCL and, as such, has a more profound effect on joint health. Still, the glucosamine-chondroitin combo is as efficient as glucosamine sulfate — hence why most manufacturers go with this powerful blend to improve your dog’s joint health.

Chondroitin Sulfate

This natural ingredient plays a protective role in cartilage health in arthritis by stopping its degradation and improving elasticity.

What Else Is in the Winning Mix?

Methylsulfonylmethane (MSM)

The combination of Glucosamine and MSM for dogs effectively reduces swelling and joint stiffness associated with arthritis. Essentially, MSM improves the range of mobility of arthritis-affected joints.

CBD/Hemp Oil

Cannabidiol (CBD), whether as an isolate or broad- and full-spectrum, has two rather convenient effects used in osteoarthritis treatment. Namely, it:

  • reduces pain
  • fights joint inflammation

Hyaluronic Acid (HA)

Hyaluronic Acid is the perfect addition to a quality formula. It lubricates joints and decreases joint damage and pain caused by friction. As a natural substance, HA is found in vast concentrations inside a healthy dog’s joints. Yet, when arthritis strikes, it diminishes and loses its effectiveness.


This widely used food spice contains a powerful natural antioxidant called curcumin, as well as other beneficial agents called curcuminoids. Turmeric is broadly employed for treating heart disease as well as cancer. The mix of glucosamine and turmeric for dogs reduces inflammation, pain, and joint rigidness.

Eggshell Membrane

Shown to reduce joint pain and improve function, taking frequent doses of the eggshell membrane leads to long-lasting healing effects. Because of this, it is featured in the ingredient list of many glucosamine supplements.

Vitamins and Minerals

Certain minerals like calcium, boron, and magnesium are an inseparable part of the formula. They are responsible for healthy bones and cartilages to help restore and preserve bone and joint integrity.

Manganese promotes joint and hip health by stopping the aging process and strengthening ligaments. On the other hand, Zinc adjusts the immune response to reduce inflammation and thus protect joints from becoming inflamed.

Fatty Acids

There’s an increasing trend of formulas containing glucosamine and fish oil for dogs, and for a good reason too! Namely, omega-3 fatty acids play a massive part in joint lubrication and fighting off inflammation.

When it comes to glucosamine supplements for dogs, fatty acids are usually derived from fish or krill oil. Among these, fatty acids EPA and DHA are considered best for fighting arthritis.

Avocado Soybean Unsaponifiables (ASU)

Defined as a combination of Avocado/Soybean Unsaponifiables, ASU powder has been shown to have protective properties and prevent inflammation from damaging the cartilage of dog joints. Therefore, dogs at risk of developing arthritis should have glucosamine containing ASU or other similar ingredients effective in cartilage protection.

Green-Lipped Mussel (GLM)

This shellfish from New Zealand is used to treat every type of cartilage and bone disease. In essence, it reduces inflammation, pain, and stiffness in joints. GLM contains fatty acids and glycosaminoglycans (GAGs) that the body uses to repair and build connective tissue and cartilage.

GLM also promotes joints’ flexibility and elasticity, which is why GLM is a common ingredient in many trusted supplements with glucosamine.

Yucca Schidigera

The Yucca plant has been traditionally used by Native Americans to treat joint pain. And the same applies to our pets.

Chemists discovered high concentrations of saponins and polyphenolics in the extract of this plant. These are proven to have pain-soothing effects and help reduce joint inflammation.

Finding the Best Dose — Advanced Dosage Guide

The quantity of glucosamine depends on several factors:

  • Age
  • Breed size
  • Health condition
  • The chemical form of glucosamine
  • Presence of other compounds

Glucosamine supplements for our fur babies can be found in many forms like food bars, liquids, shots, pills, chewables, or powdered glucosamine.

Given this diversity and the effects of other active and inactive ingredients on glucosamine absorption, the effectiveness of glucosamine is different for each of these supplements. Hence, the dosing plan will be different for all of them as well. For example, a glucosamine liquid for dogs is more readily absorbed in the dog’s body than soft chews. Therefore, the dosage per mg of glucosamine will be lower than chews.

Furthermore, if your dog suffers from other chronic ailments in addition to arthritis, you should consult with a veterinarian to make a suitable dosage plan. It might so happen that they require more or less of the usual quantity. The basic recommended glucosamine dosage for dogs is 10mg–30mg of glucosamine HCL per pound of dog weight, depending on the stage of their treatment.

In the initial period of arthritis treatment (4–6 weeks), 20mg–30mg of glucosamine per pound of dog weight is given to cause a buildup of glucosamine in the body. In the prophylactic and so-called maintenance period (after the initial period), this dose is reduced to 10mg per pound of the dog’s weight.

What Else Can You Do to Help Your Dog?

By finding and purchasing a quality glucosamine product, you can help your dog deal with arthritis and hip dysplasia. Still, there are other things that you can do to speed up the healing process.

Chiropractic adjustments and massage are not just reserved for humans. If you have access to these therapies for your dogs, don’t hesitate to use them. Choosing the best quality dog food rich in enzymes, vitamins, minerals, and fatty acids can also arm your dog for the fight against arthritis.

And finally, take your dog out on frequent walks and play with them as regular exercise will help them maintain a healthy range of joint motions.

Frequently Asked Questions

Does glucosamine really work?

Glucosamine is a widely used supplement for both humans and dogs to treat degenerative diseases in joints. Scientific evidence shows that glucosamine promotes the repair of damaged cartilage tissue in joints in three distinct ways.

Firstly, glycosaminoglycans such as glucosamine are the building blocks of cartilage. Hence, glucosamine supplements provide the necessary nutrients for joint repair. Secondly, glucosamine speeds up the regenerative processes in joints. And finally, it has been proven that glucosamine has mild anti-inflammatory effects.

What is the best glucosamine option for dogs?

Depending on the dog’s overall health, age, size, it should be the one that is sufficiently concentrated and bioavailable to provide positive effects. The entourage and compensating effects of other active ingredients such as MSM are also significant.

In addition, the source of glucosamine, its purity, and its chemical form also play a role in the effectiveness of glucosamine supplements. For example, it is believed that the glucosamine sulfate for dogs is more or equally effective as the combo of glucosamine hydrochloride with chondroitin, despite scientific evidence confirming this is not entirely so.

Studies have also proved that the liquid form of glucosamine is more easily absorbed — hence why it’s more efficient than hard or chewable glucosamine.

How much glucosamine should I give my pet?

Different glucosamine and chondroitin supplements contain various concentrations of these beneficial substances. How much your dog needs depends on its size and the severity of its condition.

Other active ingredients also play a role in dosing the supplements since they can either work in synergy with the glucosamine and chondroitin or work to counteract their effects. This is why you should always follow the instructions provided by the product’s brand on how much glucosamine you can give to your dog according to their breed size and health condition.

Another thing worth noting is the need to consult with a vet first. Determining the severity of your dog’s health condition and the eventual interference with other medications is crucial.

The most recommended glucosamine dosage for dogs is 10mg per pound of the dog’s weight per day or 15mg per kg. However, this amount is doubled in the first 4–6 weeks of the treatment (initialization period), for the concentration to accumulate in the tissue.

Daily dosage for the initial period (4–6 weeks)
Dog Weight (lbs) Glucosamine Hydrochloride (mg) Chondroitin Sulfate (mg)
5–25 500 400
25–50 1,000 800
50–100 1,500 1,200
100+ 2,000 1,600

What are the side effects of glucosamine?

If the vet’s or manufacturer’s recommendations are followed, glucosamine side effects should be extremely rare in otherwise healthy pets. However, you should not give glucosamine to dogs with a liver condition, diabetes, or other chronic ailments without prior consultation with a vet.

Dogs can also be allergic to glucosamine, especially to the one that is shellfish-derived, if it hasn’t been adequately purified. The symptoms include licking (itchiness), bald spots on the fur, and digestive disturbances.

If your dog is allergic to shellfish, you can search for a plant-derived vegetarian or vegan glucosamine products. Other side effects include fatigue, insomnia, excessive thirst and urination, digestive symptoms such as vomiting, diarrhea, skin infections, and even diabetes.

Glucosamine overdose in dogs is also extremely rare. Yet, if for some reason it does happen, your dog will require immediate medical attention. Hence, it is wise to have a proper health care plan for your dog in place.

Can glucosamine cause liver damage?

In exceptional cases of glucosamine overdose in dogs, liver function parameters can go off the grid, indicating liver damage.

In an overdose, your dog might develop jaundice alongside digestive symptoms such as vomiting, diarrhea, or stomach cramping and gas. This is why large quantities are not recommendable for dogs with any kind of liver condition.

How long does glucosamine take to work?

Glucosamine remains in your pet’s blood 1–3 hours after taking it. However, the concentration has to build up before seeing any noticeable effect. How fast this will take depends on the dose, among other factors (like the stage of the disease).

Furthermore, cartilage damage requires more time to heal. Usually, the very first results of glucosamine and chondroitin treatment can be seen only 4–6 weeks from the moment you start giving your dog its daily dose.

Can I give too much glucosamine to my dog?

Glucosamine is relatively safe for dogs, so it is not easy to go overboard with the dosage to the extent that will put your dog’s health in peril.

According to one study, the dosage that is within the range of 159mg–2700mg per kg of their weight is safe for use, even if administered daily for 365 days in a row.

Nevertheless, giving your dog too much glucosamine will not speed up the process of healing. In fact, it can cause some severe side effects and even poisoning in extreme cases. Hence, it would be better for your dog if you simply stuck with the recommendations provided by the brand.

The Bottom Line

As you can see from our top picks, there are plenty of options to choose from if you want to support your dog’s hip and joint health.

As with humans, prevention is key. Unfortunately, treating an already existing condition is much harder and more cumbersome, especially for dogs. Hence, to considerably increase their quality of life, you should give your pup only the best glucosamine for dogs.

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